Small molecules which mimic Cycloheximide treatment
Canned Analysis
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General Information
AccessionDCA00012336
TitleSmall molecules which mimic Cycloheximide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Cycloheximide treatment in the MCF-7 BREAST CANCER cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d2b4e467bea600fb8dc8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3059
Cell TypeMCF-7 BREAST CANCER cell line
Drug NameCycloheximide
Organismhuman
PubChem CID6197
SMILES IDCC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM213330, GSM213331, GSM213332, GSM213333
Perturbed SamplesGSM213322, GSM213323, GSM213324, GSM213325
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8597
Gene Expression Omnibus
Estradiol effect on breast cancer cell line in the absence of protein synthesis
14
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