Small molecules which mimic Estradiol treatment
Canned Analysis
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General Information
AccessionDCA00012348
TitleSmall molecules which mimic Estradiol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Estradiol treatment in the MCF-7 breast cancer cells - 24 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e511e467bea600fb95e8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3241
Cell TypeMCF-7 breast cancer cells - 24 Hours
Drug NameEstradiol
DrugBank IDDB00783
Organismhuman
PubChem CID5757
SMILES IDCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM659813, GSM659814, GSM659815
Perturbed SamplesGSM659816, GSM659817, GSM659818
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26834
Gene Expression Omnibus
Estrogen or insulin-like growth factor I stimulated MCF-7 breast cancer cells: time course
14
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