Small molecules which mimic Estradiol treatment
Canned Analysis
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General Information
AccessionDCA00012350
TitleSmall molecules which mimic Estradiol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Estradiol treatment in the eralpha cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d961e467bea600fb90c0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2734
Cell Typeeralpha
Drug NameEstradiol
DrugBank IDDB00783
Organismhuman
PubChem CID5757
SMILES IDCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM19191, GSM19291
Perturbed SamplesGSM19292, GSM19293
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1153
Gene Expression Omnibus
Estradiol effect on osteosarcoma cells expressing estrogen receptor alpha or beta: time course
14
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