Small molecules which reverse Fluorouracil treatment
Canned Analysis
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General Information
AccessionDCA00012361
TitleSmall molecules which reverse Fluorouracil treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Fluorouracil treatment in the hme-cc cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d6d2e467bea600fb8f9a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2740
Cell Typehme-cc
Drug NameFluorouracil
DrugBank IDDB00544
Organismhuman
PubChem CID3385
SMILES IDC1=C(C(=O)NC(=O)N1)F
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM11708, GSM11735
Perturbed SamplesGSM11680, GSM11698
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1647
Gene Expression Omnibus
Breast cancer cell lines response to chemotherapeutic drugs: time course
28
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