Small molecules which reverse Folic acid treatment
Canned Analysis
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General Information
AccessionDCA00012369
TitleSmall molecules which reverse Folic acid treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Folic acid treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d74be467bea600fb8fd2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2748
Drug NameFolic acid
DrugBank IDDB00158
Organismhuman
PubChem CID6037
SMILES IDC1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)N=C(N3)N
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM440157, GSM440158, GSM440159, GSM440160, GSM440161, GSM440162, GSM440163, GSM440164, GSM440165, GSM440166, GSM440167
Perturbed SamplesGSM440168, GSM440169, GSM440170, GSM440171, GSM440172, GSM440173, GSM440174, GSM440175, GSM440176, GSM440177
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE17635
Gene Expression Omnibus
Folic acid effect on endothelial progenitor cells of type 1 diabetes patients
7
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