Small molecules which mimic Glipizide treatment
Canned Analysis
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General Information
AccessionDCA00012370
TitleSmall molecules which mimic Glipizide treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Glipizide treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d6e6e467bea600fb8fa4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2749
Drug NameGlipizide
DrugBank IDDB01067
Organismmouse
PubChem CID3478
SMILES IDCC1=NC=C(N=C1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM45690, GSM45691, GSM45692, GSM45693
Perturbed SamplesGSM45698, GSM45699, GSM45700, GSM45701
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE2431
Gene Expression Omnibus
Candidate calorie restriction mimetic drugs effect on the liver
14
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