Small molecules which reverse Isotretinoin treatment
Canned Analysis
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General Information
AccessionDCA00012391
TitleSmall molecules which reverse Isotretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Isotretinoin treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ef2be467bea600fb9a58
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2772
Drug NameIsotretinoin
DrugBank IDDB00982
Organismhuman
SMILES IDC/C(=C\C=C\C(=C/C(=O)O)\C)/C=C/C1=C(C)CCCC1(C)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM263915, GSM263916, GSM263917
Perturbed SamplesGSM263918, GSM263919, GSM263920
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10432
Gene Expression Omnibus
13-cis retinoic acid effect on SEB-1 sebocyte cell line
12
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