Small molecules which mimic Medroxyprogesterone acetate treatment
Canned Analysis
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General Information
AccessionDCA00012394
TitleSmall molecules which mimic Medroxyprogesterone acetate treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Medroxyprogesterone acetate treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1da1ae467bea600fb9110
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2779
Drug NameMedroxyprogesterone acetate
DrugBank IDDB00603
Organismmouse
SMILES IDO=C1CC[C@]2(C(=C1)[C@@H](C)C[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@]2(OC(=O)C)C(=O)C)C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM262682, GSM262683, GSM262684, GSM262685, GSM262686, GSM262687
Perturbed SamplesGSM262676, GSM262677, GSM262678, GSM262679, GSM262680, GSM262681
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE10392
Gene Expression Omnibus
Medroxyprogesterone acetate effect on the pregnant cervix
7
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