Small molecules which reverse Deltamethrin treatment
Canned Analysis
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General Information
AccessionDCA00012415
TitleSmall molecules which reverse Deltamethrin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Deltamethrin treatment in the Frontal Cerebral Cortex - 0.3mg/kg cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e34ee467bea600fb9522
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3420
Cell TypeFrontal Cerebral Cortex - 0.3mg/kg
Drug NameDeltamethrin
Organismrat
PubChem CID40585
SMILES IDCC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Br)Br)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM190915, GSM195231, GSM195232, GSM195233, GSM195234, GSM195235, GSM195236, GSM195237, GSM195238, GSM195239, GSM195240, GSM195241
Perturbed SamplesGSM195276, GSM195278, GSM195280, GSM195281, GSM195283, GSM195285, GSM195286, GSM195288
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE7955
Gene Expression Omnibus
Deltamethrin and permethrin effect on the frontal cerebral cortex: dose response
42
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