Small molecules which mimic Propofol treatment
Canned Analysis
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General Information
AccessionDCA00012426
TitleSmall molecules which mimic Propofol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Propofol treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e1aae467bea600fb9468
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2804
Drug NamePropofol
DrugBank IDDB00818
Organismhuman
PubChem CID4943
SMILES IDCC(C)C1=C(C(=CC=C1)C(C)C)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM99239, GSM99244, GSM99247, GSM99261, GSM99274, GSM99285, GSM99291, GSM99295, GSM99301, GSM99303
Perturbed SamplesGSM99241, GSM99246, GSM99249, GSM99265, GSM99277, GSM99287, GSM99292, GSM99296, GSM99302, GSM99304
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4386
Gene Expression Omnibus
Sevoflurane and propofol effect on the heart during off-pump coronary artery bypass graft surgery
14
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