Small molecules which mimic Sevoflurane treatment
Canned Analysis
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General Information
AccessionDCA00012428
TitleSmall molecules which mimic Sevoflurane treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Sevoflurane treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e206e467bea600fb9490
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2816
Drug NameSevoflurane
DrugBank IDDB01236
Organismhuman
PubChem CID5206
SMILES IDC(OC(C(F)(F)F)C(F)(F)F)F
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM99229, GSM99252, GSM99255, GSM99258, GSM99268, GSM99280, GSM99289, GSM99293, GSM99298, GSM99305
Perturbed SamplesGSM99235, GSM99253, GSM99257, GSM99259, GSM99271, GSM99282, GSM99290, GSM99294, GSM99299, GSM99306
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4386
Gene Expression Omnibus
Sevoflurane and propofol effect on the heart during off-pump coronary artery bypass graft surgery
14
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