Small molecules which reverse Carboplatin treatment
Canned Analysis
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General Information
AccessionDCA00012435
TitleSmall molecules which reverse Carboplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Carboplatin treatment in the NSCLC adenocarcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e54be467bea600fb9602
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3060
Cell TypeNSCLC adenocarcinoma cell line
Drug NameCarboplatin
DrugBank IDDB00958
Organismhuman
PubChem CID38904
SMILES IDC1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt]
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM162889, GSM162890
Perturbed SamplesGSM162893, GSM162894
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE7035
Gene Expression Omnibus
PPARgamma agonist and platinum-based drug effect on adenocarcinoma cell line
14
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