Small molecules which mimic Rosiglitazone treatment
Canned Analysis
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General Information
AccessionDCA00012436
TitleSmall molecules which mimic Rosiglitazone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Rosiglitazone treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e3fae467bea600fb956c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2811
Drug NameRosiglitazone
DrugBank IDDB00412
Organismrat
SMILES IDO=C1NC(=O)C(S1)Cc1ccc(cc1)OCCN(c1ccccn1)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM172979, GSM172980, GSM172981, GSM172987, GSM172989, GSM172990
Perturbed SamplesGSM172982, GSM172983, GSM172984, GSM172985, GSM172986, GSM172988
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7193
Gene Expression Omnibus
Rosiglitazone effect on kidneys
14
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