Small molecules which reverse Rosiglitazone effect on prdm16-deficient inguinal white adipose tissue treatment
Canned Analysis
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General Information
AccessionDCA00012445
TitleSmall molecules which reverse Rosiglitazone effect on prdm16-deficient inguinal white adipose tissue treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Rosiglitazone effect on prdm16-deficient inguinal white adipose tissue treatment in the stromal-vascular cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e318e467bea600fb950a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjustinenoel
CREEDS IDdrug:3099
Cell Typestromal-vascular cells
Drug NameRosiglitazone effect on prdm16-deficient inguinal white adipose tissue
Organismmouse
PubChem CID77999
SMILES IDCN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM860622, GSM860623
Perturbed SamplesGSM860626, GSM860627
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35011
Gene Expression Omnibus
Rosiglitazone effect on PRDM16-deficient inguinal white adipose tissue: stromal-vascular cells
28
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