Small molecules which reverse Valproic acid treatment
Canned Analysis
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General Information
AccessionDCA00012471
TitleSmall molecules which reverse Valproic acid treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Valproic acid treatment.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1df86e467bea600fb9376
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2838
Drug NameValproic acid
DrugBank IDDB00313
Organismmouse
PubChem CID3121
SMILES IDCCCC(CCC)C(=O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM234794, GSM234795, GSM234796, GSM234797
Perturbed SamplesGSM234805, GSM234806, GSM234807, GSM234808
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE9247
Gene Expression Omnibus
Histone deacetylase inhibitors effect on osteoblast differentiation
7
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