Small molecules which reverse Carboplatin (30 h) treatment
Canned Analysis
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General Information
AccessionDCA00012479
TitleSmall molecules which reverse Carboplatin (30 h) treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Carboplatin (30 h) treatment in the 36M2 epithelial ovarian cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ebd3e467bea600fb98da
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:3031
Cell Type36M2 epithelial ovarian cancer cells
Drug NameCarboplatin (30 h)
Organismhuman
PubChem CID10339178
SMILES IDC1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2]
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM341225, GSM341231
Perturbed SamplesGSM341222, GSM341228
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13525
Gene Expression Omnibus
Carboplatin effect on epithelial ovarian cancer cell line: time course
28
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