Small molecules which mimic Carboplatin treatment
Canned Analysis
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General Information
AccessionDCA00012482
TitleSmall molecules which mimic Carboplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Carboplatin treatment in the epithelial ovarian cancer cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e4f6e467bea600fb95dc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvcogliani
CREEDS IDdrug:3089
Cell Typeepithelial ovarian cancer cell line
Drug NameCarboplatin
DrugBank IDDB00958
Organismhuman
PubChem CID38904
SMILES IDC1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt]
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM341224, GSM341225, GSM341226, GSM341230, GSM341231, GSM341232
Perturbed SamplesGSM341221, GSM341222, GSM341223, GSM341227, GSM341228, GSM341229
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13525
Gene Expression Omnibus
Carboplatin effect on epithelial ovarian cancer cell line: time course
28
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