Small molecules which reverse Ethanol treatment
Canned Analysis
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General Information
AccessionDCA00012491
TitleSmall molecules which reverse Ethanol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Ethanol treatment in the hippocampus, male cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1de30e467bea600fb92e2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcandicek
CREEDS IDdrug:3038
Cell Typehippocampus, male
Drug NameEthanol
DrugBank IDDB00898
Organismhuman
PubChem CID702
SMILES IDCCO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1085665, GSM1085667, GSM1085669, GSM1085672, GSM1085675, GSM1085676, GSM1085686, GSM1085688, GSM1085690, GSM1085692, GSM1085693, GSM1085702, GSM1085703
Perturbed SamplesGSM1085666, GSM1085668, GSM1085670, GSM1085671, GSM1085674, GSM1085678, GSM1085680, GSM1085682, GSM1085683, GSM1085684, GSM1085687, GSM1085691, GSM1085697, GSM1085700
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44456
Gene Expression Omnibus
Chronic high-level alcohol consumption effect on brain: post-mortem hippocampus
14
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