Small molecules which reverse Argyrin a treatment
Canned Analysis
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General Information
AccessionDCA00012517
TitleSmall molecules which reverse Argyrin a treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Argyrin a treatment in the MCF7 breast adenocarcinoma cells - 12 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e799e467bea600fb9702
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3052
Cell TypeMCF7 breast adenocarcinoma cells - 12 Hours
Drug NameArgyrin a
Organismhuman
PubChem CID24978550
SMILES IDCCC1C2=NC(=CS2)C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(=C)C(=O)N(CC(=O)N1)C)C)CC3=CNC4=C3C(=CC=C4)OC)CC5=CNC6=CC=CC=C65
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM212654, GSM212661, GSM297803
Perturbed SamplesGSM297801, GSM297804
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8565
Gene Expression Omnibus
Argyrin A effect on MCF7 breast cancer cells: time course
14
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