Small molecules which reverse Streptozocin treatment
Canned Analysis
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General Information
AccessionDCA00012531
TitleSmall molecules which reverse Streptozocin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Streptozocin treatment in the Liver tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d9f8e467bea600fb9102
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorrcaneva
CREEDS IDdrug:3065
Cell TypeLiver tissue
Drug NameStreptozocin
DrugBank IDDB00428
Organismmouse
PubChem CID29327
SMILES IDCN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM978535, GSM978536, GSM978537, GSM978538, GSM978539, GSM978540, GSM978541
Perturbed SamplesGSM978542, GSM978543, GSM978544, GSM978545, GSM978546, GSM978547
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39752
Gene Expression Omnibus
Streptozotocin induced type 1 diabetes: liver
14
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