Small molecules which mimic Imiquimod treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012546
TitleSmall molecules which mimic Imiquimod treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Imiquimod treatment in the psoriatic skin from back cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e6d8e467bea600fb96ac
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvcogliani
CREEDS IDdrug:3073
Cell Typepsoriatic skin from back
Drug NameImiquimod
DrugBank IDDB00724
Organismmouse
PubChem CID57469
SMILES IDCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM684685, GSM684686, GSM684687
Perturbed SamplesGSM684682, GSM684683, GSM684684
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27628
Gene Expression Omnibus
Psoriasis mouse models
47
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.