Small molecules which mimic Tretinoin treatment
Canned Analysis
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General Information
AccessionDCA00012568
TitleSmall molecules which mimic Tretinoin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Tretinoin treatment in the F9 embryonal carcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e4b0e467bea600fb95bc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3084
Cell TypeF9 embryonal carcinoma cell line
Drug NameTretinoin
DrugBank IDDB00755
Organismmouse
PubChem CID444795
SMILES IDCC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM24053, GSM24054, GSM24055
Perturbed SamplesGSM24143, GSM24144, GSM24145
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1437
Gene Expression Omnibus
Embryonal carcinoma cell line response to retinoic acid or trichostatin A
14
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