Small molecules which mimic Fluticasone treatment
Canned Analysis
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General Information
AccessionDCA00012576
TitleSmall molecules which mimic Fluticasone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Fluticasone treatment in the bronchial biopsies cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e2e9e467bea600fb94f4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjustinenoel
CREEDS IDdrug:3090
Cell Typebronchial biopsies
Drug NameFluticasone
Organismhuman
PubChem CID5311101
SMILES IDCC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)SCF)O)C)O)F)C)F
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM397588, GSM397589, GSM397590, GSM397591
Perturbed SamplesGSM397596, GSM397597, GSM397598, GSM397599
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE15823
Gene Expression Omnibus
Inhaled corticotherapy effect on allergic asthma: bronchial biopsies
7
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