Small molecules which reverse Dexamethasone treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012579
TitleSmall molecules which reverse Dexamethasone treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Dexamethasone treatment in the OE-E6/7 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e2dae467bea600fb94ee
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3093
Cell TypeOE-E6/7 cells
Drug NameDexamethasone
DrugBank IDDB01234
Organismhuman
PubChem CID5743
SMILES IDCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1319897, GSM1319901, GSM1319905
Perturbed SamplesGSM1319900, GSM1319904, GSM1319908
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54608
Gene Expression Omnibus
Glucocorticoid-induced reversal of IL1b stumulated gene expression in OE-E6/7 cells
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.