Small molecules which reverse Cisplatin treatment
Canned Analysis
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General Information
AccessionDCA00012585
TitleSmall molecules which reverse Cisplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Cisplatin treatment in the NCI-H460 human lung large cell carcinoma cell line - 24 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e2fde467bea600fb94fe
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3096
Cell TypeNCI-H460 human lung large cell carcinoma cell line - 24 Hours
Drug NameCisplatin
DrugBank IDDB00515
Organismhuman
PubChem CID441203
SMILES IDN.N.Cl[Pt+2]Cl
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1034084, GSM1034085, GSM1034086
Perturbed SamplesGSM1034102, GSM1034103, GSM1034104
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42172
Gene Expression Omnibus
Effect of cigarette smoke extract, cisplatin, nicotine and/or ionizing radiation on gene expression in the NCI-H460 human lung large cell carcinoma ce...
14
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