Small molecules which reverse Decitabine treatment
Canned Analysis
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General Information
AccessionDCA00012597
TitleSmall molecules which reverse Decitabine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Decitabine treatment in the chondrocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eb27e467bea600fb988c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:3103
Cell Typechondrocytes
Drug NameDecitabine
DrugBank IDDB01262
Organismmouse
PubChem CID451668
SMILES IDC1C(C(OC1N2C=NC(=NC2=O)N)CO)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM107800, GSM107801, GSM107802
Perturbed SamplesGSM107803, GSM107804, GSM107805
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4768
Gene Expression Omnibus
DNA demethylation effect on terminally differentiated cells
21
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