Small molecules which mimic Decitabine treatment
Canned Analysis
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General Information
AccessionDCA00012600
TitleSmall molecules which mimic Decitabine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Decitabine treatment in the osteoblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ec34e467bea600fb9906
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:3108
Cell Typeosteoblasts
Drug NameDecitabine
DrugBank IDDB01262
Organismmouse
PubChem CID451668
SMILES IDC1C(C(OC1N2C=NC(=NC2=O)N)CO)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM107797, GSM107798, GSM107799
Perturbed SamplesGSM107794, GSM107795, GSM107796
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4768
Gene Expression Omnibus
DNA demethylation effect on terminally differentiated cells
21
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