Small molecules which reverse Ethanol treatment
Canned Analysis
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General Information
AccessionDCA00012607
TitleSmall molecules which reverse Ethanol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Ethanol treatment in the lung alveolar type 2 cells (Sprague-Dawley males following 6 weeks of chronic ingestion of alcohol) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eac1e467bea600fb9860
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3107
Cell Typelung alveolar type 2 cells (Sprague-Dawley males following 6 weeks of chronic ingestion of alcohol)
Drug NameEthanol
DrugBank IDDB00898
Organismrat
PubChem CID702
SMILES IDCCO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1332324, GSM1332325, GSM1332326, GSM1332327
Perturbed SamplesGSM1332328, GSM1332329, GSM1332330
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE55243
Gene Expression Omnibus
Chronic ethanol ingestion effect on lung alveolar type 2 cell
7
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