Small molecules which mimic Estradiol treatment
Canned Analysis
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General Information
AccessionDCA00012626
TitleSmall molecules which mimic Estradiol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Estradiol treatment in the Haematopoietic stem cells (male) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e9f1e467bea600fb9806
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3118
Cell TypeHaematopoietic stem cells (male)
Drug NameEstradiol
DrugBank IDDB00783
Organismmouse
PubChem CID5757
SMILES IDCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1274470, GSM1274471, GSM1274472
Perturbed SamplesGSM1274473, GSM1274474, GSM1274475
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE52711
Gene Expression Omnibus
Estrogen effect on male and female haematopoietic stem cells
14
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