Small molecules which reverse Estradiol treatment
Canned Analysis
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General Information
AccessionDCA00012629
TitleSmall molecules which reverse Estradiol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Estradiol treatment in the Hematopoietic stem cell (Female) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dbe5e467bea600fb91de
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3120
Cell TypeHematopoietic stem cell (Female)
Drug NameEstradiol
DrugBank IDDB00783
Organismmouse
PubChem CID5757
SMILES IDCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1274476, GSM1274477, GSM1274478
Perturbed SamplesGSM1274479, GSM1274480, GSM1274481
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52711
Gene Expression Omnibus
Estrogen effect on male and female haematopoietic stem cells
14
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