Small molecules which mimic Calcitriol treatment
Canned Analysis
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General Information
AccessionDCA00012644
TitleSmall molecules which mimic Calcitriol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Calcitriol treatment in the Macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1dbece467bea600fb91e0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3126
Cell TypeMacrophages
Drug NameCalcitriol
Organismhuman
PubChem CID5280453
SMILES IDCC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1276660, GSM1276661, GSM1276662
Perturbed SamplesGSM1276663, GSM1276664, GSM1276665
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52819
Gene Expression Omnibus
Mycobacterium tuberculosis H37Rv-infected macrophages response to vitamin D
14
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