Small molecules which reverse Ascorbic acid treatment
Canned Analysis
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General Information
AccessionDCA00012651
TitleSmall molecules which reverse Ascorbic acid treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Ascorbic acid treatment in the Mc3T3-E1 osteoblast (OB) cell line (50ug of ascorbic acid for 5 days) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e07be467bea600fb93e2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3132
Cell TypeMc3T3-E1 osteoblast (OB) cell line (50ug of ascorbic acid for 5 days)
Drug NameAscorbic acid
Organismmouse
PubChem CID54670067
SMILES IDC(C(C1C(=C(C(=O)O1)O)O)O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM925429, GSM925430, GSM925431
Perturbed SamplesGSM925432, GSM925433, GSM925434
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37676
Gene Expression Omnibus
Ascorbic acid effect on Mc3T3 osteoblasts
7
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