Small molecules which mimic Cisplatin treatment
Canned Analysis
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General Information
AccessionDCA00012668
TitleSmall molecules which mimic Cisplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Cisplatin treatment in the HeyC2 ovarian carcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e482e467bea600fb95a8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3144
Cell TypeHeyC2 ovarian carcinoma cell line
Drug NameCisplatin
DrugBank IDDB00515
Organismhuman
PubChem CID441203
SMILES IDN.N.Cl[Pt+2]Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1160730, GSM1160731, GSM1160732
Perturbed SamplesGSM1160733, GSM1160734, GSM1160735
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47856
Gene Expression Omnibus
Expression data from cultured human ovarian carcinoma cell lines with and without Cisplatin treatment
119
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