Small molecules which mimic Cisplatin treatment
Canned Analysis
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General Information
AccessionDCA00012670
TitleSmall molecules which mimic Cisplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Cisplatin treatment in the A2780 ovarian carcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ec82e467bea600fb992a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3145
Cell TypeA2780 ovarian carcinoma cell line
Drug NameCisplatin
DrugBank IDDB00515
Organismhuman
PubChem CID441203
SMILES IDN.N.Cl[Pt+2]Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1160736, GSM1160737, GSM1160738
Perturbed SamplesGSM1160739, GSM1160740, GSM1160741
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47856
Gene Expression Omnibus
Expression data from cultured human ovarian carcinoma cell lines with and without Cisplatin treatment
119
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