Small molecules which reverse Calcitriol treatment
Canned Analysis
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General Information
AccessionDCA00012701
TitleSmall molecules which reverse Calcitriol treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Calcitriol treatment in the Primary smooth muscle cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e42be467bea600fb9582
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDdrug:3170
Cell TypePrimary smooth muscle cells
Drug NameCalcitriol
DrugBank IDDB00136
Organismhuman
SMILES IDO[C@H]1C[C@H](O)C(=C)/C(=C\C=C\2/CCC[C@]3([C@H]2CC[C@@H]3[C@@H](CCCC(O)(C)C)C)C)/C1
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM116104, GSM116105, GSM116106
Perturbed SamplesGSM116101, GSM116102, GSM116103
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5145
Gene Expression Omnibus
Vitamin D effect on bronchial smooth muscle cells
12
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