Small molecules which mimic Carboplatin treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012710
TitleSmall molecules which mimic Carboplatin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Carboplatin treatment in the OV1002 ovarian cancer cell line - Day 14 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1edcbe467bea600fb99be
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3178
Cell TypeOV1002 ovarian cancer cell line - Day 14
Drug NameCarboplatin
DrugBank IDDB00958
Organismhuman
PubChem CID38904
SMILES IDC1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt]
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1202130, GSM1202133, GSM1202136, GSM1202178, GSM1202181, GSM1202184
Perturbed SamplesGSM1202098, GSM1202101, GSM1202104, GSM1202107, GSM1202167, GSM1202169, GSM1202171, GSM1202174
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE49577
Gene Expression Omnibus
Chemotherapy induced dynamic gene expression changes in vivo are prognostic in ovarian cancer
35
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.