Small molecules which mimic Interferon beta-1b treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012722
TitleSmall molecules which mimic Interferon beta-1b treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Interferon beta-1b treatment in the Peripheral mononuclear blood cells (NAB+) - 24 months cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e3c1e467bea600fb9554
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3185
Cell TypePeripheral mononuclear blood cells (NAB+) - 24 months
Drug NameInterferon beta-1b
DrugBank IDDB00068
Organismhuman
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM641342, GSM641346, GSM641350, GSM641354
Perturbed SamplesGSM641345, GSM641353, GSM641357
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26104
Gene Expression Omnibus
Relapsing-remitting multiple sclerosis therapy of Interferon- Betaferon or Rebif: peripheral mononuclear blood cells
42
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.