Small molecules which reverse Interferon beta-1a treatment
Canned Analysis
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General Information
AccessionDCA00012727
TitleSmall molecules which reverse Interferon beta-1a treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Interferon beta-1a treatment in the Peripheral mononuclear blood cells (NAB-) 12 months cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e3eae467bea600fb9566
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3187
Cell TypePeripheral mononuclear blood cells (NAB-) 12 months
Drug NameInterferon beta-1a
DrugBank IDDB00060
Organismhuman
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM641358, GSM641362, GSM641366, GSM641370
Perturbed SamplesGSM641364, GSM641368, GSM641372
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26104
Gene Expression Omnibus
Relapsing-remitting multiple sclerosis therapy of Interferon- Betaferon or Rebif: peripheral mononuclear blood cells
42
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