Small molecules which reverse Azathioprine treatment
Canned Analysis
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General Information
AccessionDCA00012739
TitleSmall molecules which reverse Azathioprine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Azathioprine treatment in the Colon cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e177e467bea600fb9452
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorMicrotaskManic
CREEDS IDdrug:3194
Cell TypeColon
Drug NameAzathioprine
DrugBank IDDB00993
Organismhuman
PubChem CID2265
SMILES IDCN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM948585, GSM948586
Perturbed SamplesGSM948573, GSM948575, GSM948579, GSM948583, GSM948589, GSM948590, GSM948591, GSM948592
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38713
Gene Expression Omnibus
Intestinal mucosa response to active and inactive ulcerative colitis: colon biopsies
28
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