Small molecules which mimic Hypochlorous acid treatment
Canned Analysis
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General Information
AccessionDCA00012754
TitleSmall molecules which mimic Hypochlorous acid treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Hypochlorous acid treatment in the AEC (primary airway epithelial cells) - 6 Hours with 1mM cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ee28e467bea600fb99e6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3200
Cell TypeAEC (primary airway epithelial cells) - 6 Hours with 1mM
Drug NameHypochlorous acid
Organismhuman
PubChem CID24341
SMILES IDOCl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM245430, GSM245432, GSM245440, GSM245452
Perturbed SamplesGSM245428, GSM245438, GSM245450, GSM245458
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE11630
Gene Expression Omnibus
Airway epithelial cells response to hypochlorous acid: time course
42
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