Small molecules which mimic Creatine treatment
Canned Analysis
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General Information
AccessionDCA00012764
TitleSmall molecules which mimic Creatine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Creatine treatment in the Brains of C57Bl/6J animals (fed a creatine supplemented diet for 6 months) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ee0ce467bea600fb99da
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3205
Cell TypeBrains of C57Bl/6J animals (fed a creatine supplemented diet for 6 months)
Drug NameCreatine
DrugBank IDDB00148
Organismmouse
PubChem CID586
SMILES IDCN(CC(=O)O)C(=N)N
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM115532, GSM115533, GSM115534, GSM115535, GSM115536, GSM115537, GSM115538
Perturbed SamplesGSM115526, GSM115527, GSM115528, GSM115529, GSM115530, GSM115531
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5140
Gene Expression Omnibus
Creatine effect on the brain
7
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