Small molecules which reverse Doxycycline treatment
Canned Analysis
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General Information
AccessionDCA00012769
TitleSmall molecules which reverse Doxycycline treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Doxycycline treatment in the Embryoid bodies - 12 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1edfde467bea600fb99d4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3207
Cell TypeEmbryoid bodies - 12 Hours
Drug NameDoxycycline
DrugBank IDDB00254
Organismmouse
PubChem CID5281011
SMILES IDCC1C2C(C3C(C(=O)C(=C(N)O)C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM739472, GSM739473, GSM739474
Perturbed SamplesGSM739475, GSM739476, GSM739477
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29848
Gene Expression Omnibus
bHLH transcription factor Mesogenin1 ectopic expression effect on embryoid bodies: time course
36
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