Small molecules which reverse L-arginine treatment
Canned Analysis
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General Information
AccessionDCA00012775
TitleSmall molecules which reverse L-arginine treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by L-arginine treatment in the Colon (DSS - induced colitis) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1eb94e467bea600fb98bc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3214
Cell TypeColon (DSS - induced colitis)
Drug NameL-arginine
Organismmouse
PubChem CID6322
SMILES IDC(CC(C(=O)O)N)CN=C(N)N
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM856810, GSM856811, GSM856812
Perturbed SamplesGSM856816, GSM856817, GSM856818
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34874
Gene Expression Omnibus
DSS-induced colitis model response to L-arginine supplementation
14
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