Small molecules which mimic Adenosine triphosphate treatment
Canned Analysis
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General Information
AccessionDCA00012784
TitleSmall molecules which mimic Adenosine triphosphate treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Adenosine triphosphate treatment in the AML FAB class M4 - acute myeloid leukemia lymphoblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d3d8e467bea600fb8e48
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3220
Cell TypeAML FAB class M4 - acute myeloid leukemia lymphoblasts
Drug NameAdenosine triphosphate
Organismhuman
PubChem CID5957
SMILES IDC1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM766235, GSM766237, GSM766247
Perturbed SamplesGSM766236, GSM766238, GSM766248
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30903
Gene Expression Omnibus
ATP effect on acute myeloid leukemia lymphoblasts
14
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