Small molecules which reverse Lmp-420 treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012787
TitleSmall molecules which reverse Lmp-420 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Lmp-420 treatment in the Primary chronic lymphocytic leukemia cell - 2 uM for 24 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1d3e4e467bea600fb8e4e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3222
Cell TypePrimary chronic lymphocytic leukemia cell - 2 uM for 24 Hours
Drug NameLmp-420
Organismhuman
PubChem CID497668
SMILES IDB(CCCCCN1C=NC2=C1N=C(N=C2Cl)N)(O)O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM506907, GSM506909, GSM506911, GSM506913, GSM506915, GSM506917, GSM506919, GSM506921, GSM506923, GSM506925, GSM506927, GSM506929, GSM506931
Perturbed SamplesGSM506908, GSM506910, GSM506912, GSM506914, GSM506916, GSM506918, GSM506920, GSM506922, GSM506924, GSM506926, GSM506928, GSM506930, GSM506932
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20211
Gene Expression Omnibus
Primary chronic lymphocytic leukemia cell response to purine nucleoside analog LMP-420
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.