Small molecules which mimic Nvp-tnks656 treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00012820
TitleSmall molecules which mimic Nvp-tnks656 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Nvp-tnks656 treatment in the SW480 cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e53fe467bea600fb95fc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorPascal
CREEDS IDdrug:3249
Cell TypeSW480 cancer cells
Drug NameNvp-tnks656
Organismhuman
PubChem CID27924
SMILES IDCCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1340521, GSM1340522
Perturbed SamplesGSM1340533, GSM1340534
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE55624
Gene Expression Omnibus
SW480 KRAS-mutant colorectal cancer cell line response to dual inhibition of tankyrase and MEK: time course
48
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.