Small molecules which reverse Streptozocin treatment
Canned Analysis
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General Information
AccessionDCA00012827
TitleSmall molecules which reverse Streptozocin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by Streptozocin treatment in the Islets of Balb/c mice cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e539e467bea600fb95fa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjustinenoel
CREEDS IDdrug:3248
Cell TypeIslets of Balb/c mice
Drug NameStreptozocin
DrugBank IDDB00428
Organismmouse
PubChem CID29327
SMILES IDCN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM936823, GSM936824, GSM936825
Perturbed SamplesGSM936826, GSM936827
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38215
Gene Expression Omnibus
Streptozotocin effect on pancreas of offspring of protein-restricted dams
7
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