Small molecules which mimic Curcumin treatment
Canned Analysis
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General Information
AccessionDCA00012832
TitleSmall molecules which mimic Curcumin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Curcumin treatment in the U937 cell line (monocyte) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e339e467bea600fb9518
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorPascal
CREEDS IDdrug:3259
Cell TypeU937 cell line (monocyte)
Drug NameCurcumin
Organismhuman
PubChem CID969516
SMILES IDCOC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM276209, GSM276217, GSM276225
Perturbed SamplesGSM276214, GSM276222, GSM276230
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10896
Gene Expression Omnibus
Curcumin effect on oxidatively stressed monocyte cell line: time course
28
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