Small molecules which mimic Doxorubicin treatment
Canned Analysis
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General Information
AccessionDCA00012840
TitleSmall molecules which mimic Doxorubicin treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Doxorubicin treatment in the A673 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e91de467bea600fb97aa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDdrug:3261
Cell TypeA673
Drug NameDoxorubicin
DrugBank IDDB00997
Organismhuman
PubChem CID31703
SMILES IDCC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM159856, GSM159857, GSM159858, GSM159859, GSM159860
Perturbed SamplesGSM159888, GSM159889, GSM159890
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6930
Gene Expression Omnibus
Cytosine arabinoside effect on Ewing's sarcoma cell line: time course and dose response
119
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