Small molecules which mimic Sb 216763 treatment
Canned Analysis
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General Information
AccessionDCA00012872
TitleSmall molecules which mimic Sb 216763 treatment
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by Sb 216763 treatment in the RS4.11 leukemia cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1e94be467bea600fb97be
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3266
Cell TypeRS4.11 leukemia cell line
Drug NameSb 216763
Organismhuman
PubChem CID176158
SMILES IDCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM492838, GSM492846
Perturbed SamplesGSM492847, GSM492848, GSM492849
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19736
Gene Expression Omnibus
Glycogen synthase kinase 3 inhibitor effect on MLL leukemia cells
12
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